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GnRH analogue : ウィキペディア英語版 | Gonadotropin-releasing hormone analogue
A gonadotropin-releasing hormone analogue (GnRH analogue or ''analog''), also known as a luteinizing hormone releasing hormone agonist (LHRH agonist) or LHRH analogue is a synthetic peptide drug modeled after the human hypothalamic gonadotropin-releasing hormone (GnRH). A GnRH analogue is designed to interact with the GnRH receptor and modify the release of pituitary gonadotropins FSH and LH for therapeutic purposes. Shortly after the discovery of GnRH by Nobel laureates Guillemin and Schally researchers tried to modify the GnRH decapeptide with the intent to synthesize stimulating and blocking variants. Two types of analogues have to be distinguished: ==Agonists==
(詳細はウィキペディア(Wikipedia)』 ■ウィキペディアで「Gonadotropin-releasing hormone analogue」の詳細全文を読む
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